hrp0084p2-381 | Fat | ESPE2015

Metformin in Combination with Lifestyle Changes Effectively Reduces BMI and Waist Circumference in Overweight/Obese Children and Adolescents

Smetanina Natalija , Seibokaite Adrone , Valickas Raimondas , Kuprionis Gintaras , Grigoniene Jolanta Janina , Rokaite Ruta , Vitkauskiene Astra , Albertsson-Wikland Kerstin , Verkauskiene Rasa

Background: Overweight (OW) and obesity in paediatric population has been shown to be associated with an increase in prevalence of insulin resistance and type 2 diabetes (T2D) in youth.Objective and hypotheses: The aim of this study was to assess the efficiency and safety of metformin use in combination with lifestyle changes or alone for weight management in OW and obese (OB) children and adolescents.Methods: Study included 145 10...